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Most side effects are mild and temporary, but it is important for patients to be aware of them and know how to manage them
In order to lower glucose, GIP travels to beta cells in the pancreas and activates GIP receptors (GIPr) via class-II G-protein coupled receptors causing an increase in intracellular cAMP and calcium leading to a release of insulin [3]
Hypoglycaemia patients receiving GLP-1 and GIP analogues therapy alongside sulfonylureas or insulin therapy may have an increased risk of adverse effects[511]
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