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The central mechanism involves decreased dopamine and norepinephrine signaling in the hypothalamus, where these neurotransmitters are produced and released during sexual excitation
In several studies, consistent decrease of SBP and BP-lowering occurred in the early period independent of weight loss (112114)
According to a study in The New England Journal of Medicine (source), Semaglutide helps the body regulate blood sugar and can slow the digestion process
However, research is currently being done to explore whether it can be modified so as to not cross the blood-brain barrier
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