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During a mean follow-up of 10.6 months, adults receiving an SGLT2 inhibitor had a lower risk for a CV event than those receiving a DPP-IV inhibitor (HR = 0.72
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The treatment policy estimand included all study participants randomly assigned to each treatment, using data regardless of discontinuation of study medications and/or use of additional blood glucose lowering medications during the trial (thereby reflecting the intention-to-treat principle)
Constipation : This common side effect results from slowed gastric emptying and reduced gut motility
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