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2.4 mg was the dose advanced into Phase 3 because the efficacy/tolerability ratio peaked there

Inherited molybdenum cofactor deficiency Because molybdenum functions only in the form of the Moco in humans, any disturbance of Moco metabolism can disrupt the function of all molybdoenzymes

Glutathione Supplementation Summary Oral powder (not recommended) Liposomal glutathione formulation (recommended) Inhaled GSH with a special nebulizer (recommended but need a prescription) Transdermal and lotions (variable levels of absorption) IV (most effective but also most invasive) Boost levels with selenium, ALA, NAC, and/or SAMe (recommended) Glutathione supplementation has a few rare side effects, including abdominal cramps, bloating, loose stools, gas, and possible allergic reactions such as rash

Glutathione can shift rapidly between the reduced and the oxidized state so when taken in a direct form orally it gets oxidized in the stomach, so the active form is not absorbed