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( Lancet 2023, NCT04982575 [12] ) randomised 92 adults with type 2 diabetes on metformin, with or without an SGLT2 inhibitor, 1:1:1 to CagriSema (n=31), semaglutide (n=31), or cagrilintide (n=30), all escalated to 2.4 mg, across 17 US sites over 32 weeks
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Sales of the medicine, sold as Zepbound to treat obesity and Mounjaro for diabetes, topped $36 billion last year as it took market share away from Novo Nordisk's more established Wegovy/Ozempic treatment
Personalized Approach: Genetics and Thyroid Sensitivity The PlexusDx Precision Peptide Genetic Test analyzes GIPR, FTO, and MC4R variants that relate to GLP-1 and related signaling pathways
