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The article explains that GLP-1 agonists slow gastric emptying and reduce appetite, so overall fluid and nutrient intake can drop if hydration is not deliberately maintained

Combination pharmacotherapy for obesity is not currently recommended outside of clinical trials

Activation of microglia is a widespread feature of neurodegeneration that appears in different neurodegenerative diseases 23

She hopes to see people with obesity, particularly those with medical complications, gain better access to the approved drugs and in settings where they can be monitored by their doctors to ensure that the benefits outweigh the risks