long term effects of glp 1 use New Research on GLP-1s & Bone Health 🦴 ​A new large-scale study has raised questions about the long-term GLP-1 receptor agonists (like Ozempic and Wegovy). While these medications are revolutionary Common, uncommon, and rare side

While Ipamorelin's human data is limited (primarily PK/PD studies and a discontinued Phase II for postoperative ileus), the dose-dependent acute stimulation aligns with 3-10 fold increases in peak GH, with effects lasting approximately 2-3 hours per administration (PMID: 10496658)

Although experience with GLP-1 agonists in patients with obesity and inflammatory skin diseases is currently scarce, the promising results reported suggest they may offer a useful tool for managing obesity

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Its activity as a ghrelin mimetic has also been examined in a rodent model of postoperative ileus