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It is advisable not to consume higher doses to enjoy the health benefits
If results indicate inferior PK propertiessuch as high clearance, short half-life (t 1/2 ) and/or low bioavailabilityPD effects will likely be sub-optimal
I have tried everything with zero results and have been completely frustrated
The more clinically important question is how often this produces meaningful perioperative harm, which patients are at highest risk, and how clinicians should balance aspiration prevention against the metabolic, cardiovascular, logistical, and equity-related consequences of withholding therapy
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