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Phase 2 Trial: Design and Weight-Loss Findings Moreover, The principal Phase 2 monotherapy study, identified as NCT06230523 , was a 48-week randomized, double-blind, placebo-controlled trial conducted in the United States
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GH therapy in older adults has been shown to increase lean mass, reduce fat mass, and improve subjective quality of life scores. Rudman, D
Meta-analyses have shown that the amount of weight regained after stopping treatment is typically proportional to the initial weight loss, and lifestyle interventions become increasingly difficult to maintain once the medication is discontinued ( 10 Expanding the use of GLP-1RAs to treat substance use disorders To date, only a limited number of clinical trials have evaluated the effectiveness of GLP-1RAs for substance use disorders, yet initial findings are encouraging
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