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Progress in Cardiovascular Diseases, 56 (4), 441447
While a formal non-responder protocol utilizing measurable criteria (e.g., less than 3% body weight loss in 90-days) was not identified via public documentation, beginning discussions regarding potential non-responder status with your assigned clinician at 3-month intervals is an action item
These may be harder to measure, but the key is that such therapies aim for more cumulative long-term effects
Furthermore, another study highlighted GLP-1 RAs direct impact on the brain, especially the hypothalamus 40
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