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The actin-binding domain sequence captured in TB-500 , the LKKTETQ motif and surrounding sequence and was identified through systematic deletion and substitution analysis of Thymosin Beta-4 as the minimal region required for G-actin binding and for recapitulating the full biological activity of the intact protein in cell migration, wound healing, and angiogenesis assays

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Researchers looking into this peptide may also review HGH-focused compounds when exploring broader peptide categories within experimental environments