An important model to study the consequences of systemic carnitine deficiency is the homozygous OCTN2 null mouse, in which OCTN2 function is abolished by the missense mutation L352R
Encapsulated drugs within liposomes have been found to degrade or lose their activity before exerting their intended medicinal effects [32]
2007: A small, multicenter clinical study among 56 people with neuropathy associated with antiretroviral drug therapy showed that receiving 500 mg of acetyl-L-carnitine twice daily intramuscularly for two weeks, followed by 1,000 mg twice daily orally for 6 weeks, reduced pain by 0.89 points (on a 010 scale) compared to placebo
It is thought that glutathione may be beneficial in treating diseases that involve oxidative stress, such as heart disease, cancer, diabetes, Alzheimer's disease, Parkinson's disease, and liver disease