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The bottom line on safety: Because retatrutide is investigational, the only appropriate way to take it is within a supervised clinical trial
These include: Acute gallbladder disease (added to warning label in March 2022) Acute problems Acute pancreatitis Diabetic retinopathy complications in patients with type 2 Diabetes Gastrointestinal obstruction Ileus (added to the warning label in September 2023) Heart rate increase Hypoglycemia Possible thyroid tumors, including cancer Severe allergic reactions and hypersensitivity reactions, including anaphylaxis and angioedema Suicidal thoughts or behavior If you are taking Wegovy or any other GLP-1 drug like Mounjaro or Rybelsus , contact your doctor if you experience new or worsening side effects
doi: 10.5937/arhfarm73-42160 573 WastykHCPerelmanDTopfMFragiadakisGKRobinsonJLSonnenburgJLet al
GLP-1 agonist evidence includes large phase 3 trials with thousands of participants followed for 52+ weeks
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