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People with vegetarian or vegan diets (as B12 is mainly found in animal products)
Intravenous administration of lipoic acid at doses of 600 mg/day for three weeks (112) and oral lipoic acid at doses as high as 1,800 mg/day for six months (113) and 1,200 mg/day for two years (76) did not result in serious adverse effects when used to treat diabetic peripheral neuropathy
(PubMed) Obeid R, Derbyshire E, Schon C
Deficiency is widespread, with peer-reviewed research describing it as a global health concern affecting populations across all age groups and geographies (Cashman et al., American Journal of Clinical Nutrition , 2016
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