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Researchers observed that GHK-Cu influences expression of over 4,000 human genes based on microarray studies, with significant effects on genes involved in collagen synthesis, metalloproteinase regulation, antioxidant defense (SOD, glutathione), and growth factor signaling (TGF-, VEGF, FGF)

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(3) Raun K, Hansen BS, Johansen NL, Thgersen H, Madsen K, Ankersen M, Andersen PH

Regular physical activity, including 150 minutes of moderate aerobic exercise and resistance training 2-3 days weekly, enhances metabolic health through improved insulin sensitivity and glucose utilization