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405 Differential expression analysis showed downregulation of adhesion/metabolic proteins and upregulation of immune evasion markers, motility proteins, and chromatin regulators, collectively driving invasive and resistant phenotypes

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NRF2 activity is also regulated by the availability of many binding partners, including a group of bZIP bi-directional transcription regulators named sMaf proteins (MafF, G and K) [200, 201] which, when bound to NRF2, under OS, favor its maintenance inside the nucleus thereby enhancing its activity [202]