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Clinical evidence shows substantial benefit even at lower doses
6 8 Second, the clinical consequences of the metabolic core are serious and long-term: impaired glucose tolerance, markedly elevated risk of type 2 diabetes, atherogenic dyslipidemia, MASLD, and cardiovascular risk factors cluster in PCOS
By highlighting the key challenges and emerging research directions, this review aims to provide valuable insights into the development of novel proteostasis-targeted therapies
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