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A deficiency or lack of Vitamin B12 is quite common in the over 65s, those diagnosed with pernicious anaemia, and in anyone who follows a vegan, strict vegetarian, or extreme/fad/restricted diet for a long time without taking a B12 supplement or eating fortified foods

substrate for sirtuins and PARPs Redox states: Cycles between NAD+ (oxidised) and NADH (reduced) Vial size: 1000 mg Format: Lyophilized powder Studied applications Mitochondrial-function research Sirtuin-pathway studies (SIRT1, SIRT3 and related) DNA-repair mechanism and PARP-pathway research Redox biology and cellular-senescence models Reference-standard use and enzyme cofactor in assay development Quality & trust 99% HPLC purity, third-party tested Mass spectrometry identity confirmation LAL endotoxin testing on every batch Batch-specific Certificate of Analysis included COA shown in the product gallery cGMP manufactured in Dallas, Texas (USA) USA same-day shipping (orders before 2pm CT M-F) Free domestic shipping on orders over $200 Storage & handling Store refrigerated at 28C, protected from light and heat NAD+ is light-sensitive and degrades faster in solution than in lyophilized form Reconstitute with bacteriostatic water for laboratory preparation

For example, some medications cant be given orally because acid and enzymes in the stomach would destroy them