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Practical Considerations for Clinicians For healthcare providers at LifeRx.md and beyond, incorporating GLP-1 receptor agonists into treatment plans for obese patients requires careful patient selection and monitoring

In contrast, retatrutide, a newer medication, has a tri-agonist approach, targeting GLP-1, GIP, and glucagon

While rare cases of acute liver injury and heightened liver enzymes have been reported, clinical trial evidence suggests the medication can actually improve liver function in many patients, particularly those with fatty liver disease

In addition, WAYT-less decreases body mass and lowers insulin resistance