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Patients who maintain some form of treatment continuity, whether through medication switches, restarts, or regular contact with dietitians and weight management specialists, appear to fare better than trial conditions would predict

The programme also included a long-term safety trial, trials to evaluate the use of orally administered semaglutide in individuals with moderate renal impairment and as add-on to insulin as well as a cardiovascular outcome trial (CVOT) to evaluate the CV safety profile

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