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Who Can Benefit Most from B12 Shots
Navitoclaxs precursor, ABT737, a BH3 mimetic, prevents the interaction between anti-apoptotic and pro-apoptotic proteins, also leading to senescent cell apoptosis [105]
Despite this progress, translation beyond preclinical systems remains limited by insufficient standardisation of synthesis and purification protocols, significant batch-to-batch variability, and incomplete understanding of pharmacokinetics, long-term toxicity and biodistribution
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