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At the 800 mg dose, peak sitagliptin plasma concentrations were approximately 11 times higher than the peak concentrations following a 100 mg dose
Combination of PIO with SLGT2 inhibitors Preclinical evidence The possible activities of ipragliflozin (IPRA), PIO or their combination on a variety of diabetic features (IR, hyperinsulinemia, obesity, dyslipidemia) and the progression to NASH were explored after their administration to high-fat diet-fed KK/A y T2D mice [113]
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As a result, we combined the two types of medications for the rest of the paper to increase the sample size
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