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GLP-1 Receptor Agonists: Mechanisms of Action and Class Overview Mechanism of Action: GLP-1 receptor agonists (incretin mimetics) work by mimicking the action of endogenous GLP-1, a gut hormone (incretin) that is released in response to nutrient intake
When discussing weight loss medicines, it is helpful to ask your GP or specialist about: Currently licensed and NICE-approved options available to you on the NHS or privately Eligibility criteria for specific treatments and what monitoring would be required Realistic expectations regarding weight loss outcomes, timescales, and the importance of lifestyle changes alongside medication Potential side effects , including gastrointestinal symptoms commonly associated with GLP-1 receptor agonists, and how these are managed If you experience any suspected side effects from a weight management medicine, you can report these directly to the MHRA via the Yellow Card Scheme (available at yellowcard.mhra.gov.uk)
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