no side effects from semaglutide In four recent placebo-controlled clinical trials, dysesthesia, an unpleasant sensation that's perceived on or under the skin, was reported as a effect of the GLP-1 agonist in 5-23% of recipients Ozempic side effects: FDA says

Over time, pharmacological engineering enabled: Short-acting injectables (e.g., exenatide) Long-acting once-weekly injectables (liraglutide, semaglutide) Multi-target incretin therapies (tirzepatide) Oral peptide formulations and now oral small molecules The most recent breakthrough is the development of orally available GLP-1 receptor agonists, including: Orforglipron (Lilly) Elecoglipron (AstraZeneca) These compounds eliminate the need for injection and could dramatically expand accessibility and adherence in obesity and diabetes populations

Cost ranges from $15 to $60 depending on quality and brand

Its certainly something to bear in mind when consulting your patients, particularly where they may have been receiving botox prior to starting weight loss medication

When given orally, semaglutide is dosed differently as absorption and delivery are different from injectable semaglutide (more on that below)