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A control tripeptide (L-glutamyl-L-histidyl-L-proline) was inactive in the same system, indicating that the effect is sequence- and copper-coordination-specific rather than a general copper-delivery phenomenon

The container requires no vapor barrier to maintain the proper drug concentration

The microbiome and irritable bowel syndrome - a review on the pathophysiology, current research and future therapy

For example, mutations in RRM2B can cause MNGIE-like symptoms by disrupting the docking interface of the ribonucleoside reductase small subunit homodimer, thereby impairing ribonucleoside reductase activity and damaging the mitochondrial nucleotide pool, which leads to mtDNA depletion