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(PDF 413 kb) Rights and permissions About this article Cite this article Jazayeri, A., Rappas, M., Brown, A
It is the only amino acid whose side chain terminates in a free sulfhydryl group, and that single thioljust one sulfur atom and one protonis what makes cysteine the rate-limiting precursor for glutathione synthesis, the structural lynchpin of disulfide bonds that hold secreted proteins and antibodies in their functional conformations, the catalytic nucleophile in the active sites of cysteine proteases and thioredoxin reductases, and the metabolic sensor whose oxidation state reports the redox poise of the entire cell
The safety and effectiveness of combining medications will depend on a patients individual health conditions and the specific medications involved
Endocrinology 156 , 35383547 (2015)
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