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Oral / intranasal bioavailability, oral bioavailability is essentially zero (peptide-bond hydrolysis in GI tract)
These materials can be incorporated with peptides cleaved by specific enzymes, such as trypsin and cathepsin, leading to selective drug or imaging agent activation/release
If you wear makeup, choose non-comedogenic, oil-free products and remove them thoroughly each evening
Arendt J (1988)
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