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Consistent with the experiments in vitro , RSL3 downregulated the elevated GPX4 in residual tumors, not FTH1 ( Figure 5I )

Also, statins reduce ovarian androgen production by preventing the creation of androgen from theca cells and also lower total cholesterol by regulating 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase that is necessary for cholesterol synthesis [46, 60]

Lead time was close to what they estimated, which made planning easier