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When heat-induced damage exceeds the repair capacity of HSPs, the cell may undergo apoptosis (Williams et al., 2019)
5 , following studies analyzing the influence by treating together or alone with nitric oxide inhibitor, N -nitro-l-arginine methyl ester (L-NAME) or nitric oxide precursor, L-arginine all showed that the nitric oxide modulation is involved in the healing effect of BPC 157 in different tissue injuries
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