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This finding, more pronounced in patients with autonomic dysregulation, is interpreted as indicative of increased oxidative stress and therefore may represent an epiphenomenon providing evidence for reverse causality in the UA-PD relationship

The FDA-approved prescribing information for tirzepatide explicitly states that "there are no data on the presence of tirzepatide in human milk, the effects on the breastfed infant, or the effects on milk production." This absence of data reflects the exclusion of pregnant and breastfeeding individuals from clinical trials, a common practice that creates knowledge gaps for this population

However, like all medications, these are not perfect

10.1002/alz.14346 Alzheimers Dement