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Claimed outcome NAD+ changes Evidence level Cell and animal evidence What research currently shows Blocking NNMT can preserve nicotinamide, a building block used to make NAD+
NNMT is an enzyme that works in your cells to manage energy and metabolism
Extended treatment continued to limit body weight gain and white adipose tissue mass, lowered total plasma cholesterol, and showed measurable accumulation in adipose tissue consistent with the compounds lipophilic profile
NAD+ supplementation adds NAD+ from the outside
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