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Under cystine-starved conditions, GSH supplementation rescued the phosphorylation of p70S6K (T389) and S6 (S235/236) of the mTORC1 pathway and relieved the induction of phospho-GCN2 (T899), phospho-eIF2 (S51) and ATF4 of the ISR system (Fig
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And its incredibly vulnerable during this transition
Conflict of Interest DP declared consulting, advisory role or lectures from AstraZeneca, Bristol-Myers Squibb, Boehringer Ingelheim, Celgene, Daiichi Sankyo, Eli Lilly, Merck, Novartis, Pfizer, prIME Oncology, Peer CME, Roche
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