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A related study showed that after doxorubicin was injected into mice, expression of GPX4 was downregulated, mitochondrial lipid peroxidation was caused by the DOX-Fe 2+ complex, and mitochondria-dependent ferroptosis was the main cause of DIC

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Therefore, we performed pharmacokinetic studies of BPC157 in beagle dogs following single IV administration at a dose of 6 g/kg, single IM administration at doses of 6, 30, or 150 g/kg, and repeated IM administration at a dose of 30 g/kg for seven consecutive days