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The ligation reaction of CoA with AdA/AA is catalyzed by ACSL4 to form COA-AdA/AA intermediate, which subsequently undergoes esterification with lysophospholipids by LPCAT3
The peptide increases survival of enteric neurons, enhances enteric glial cell proliferation, and modulates enteric serotonin release
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These findings suggest that the combined use of astaxanthin and retinol can effectively address skin aging, provided it is paired with photoprotection
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