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Kinetic parameters were determined using LineweaverBurk plots using KaleidaGraph 4 (Synergy Software, least squares best fit of data and varying concentrations of one substrate while maintaining the concentration of other substrates
61:104-108 Masayuki Ikeda, Makoto Asai, Takahiro Moriya, Masami Sagara, Shojiro Inou, Shigenobu Shibata, Methylcobalamin amplifies melatonin-induced circadian phase shifts by facilitation of melatonin synthesis in the rat pineal gland, Brain Research, Volume 795, Issues 12, 8 June 1998, Pages 98-104, ISSN 0006-8993, Carmen Wheatley Cobalamin in inflammation III glutathionylcobalamin and methylcobalamin/adenosylcobalamin coenzymes: the sword in the stone
Liposomal supplementation has been a common way of delivering drugs for many years, with no associated safety issues
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