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It was included as a tertiary agent in the 2017 edition of the multi-agency clinical guidelines for the treatment of hypertension (Whelton et al, 2018), but was no longer mentioned in the 2025 AHA/ACC multisociety hypertension guidelines (Jones et al, 2025)
But the real prize was a once-weekly formulation that would transform convenience and compliance
Kwon S-K, Hirabayashi Y, Polleux F
Diet and GLP-1 problems can turn into a vicious cycle
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