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These agents selectively modulate antibody production, reducing IgG and IgM levels while enhancing IgE production (112, 113)
While semaglutide is administered once weekly, tirzepatide offers a slightly broader titration window
In one meta-analysis of obese men, testosterone therapy added to diet-induced weight loss resulted in significantly greater visceral fat reduction and improved lean mass preservation
Abnormal gut microbiota in patients with T2DM and obesity promote abnormal intestinal permeability with the development of endotoxemia and systemic complications (Venegas-Borsellino et al
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