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Clinical guidance from the North American Menopause Society emphasizes that symptom improvement with hormone therapy is progressive and depends on dose, formulation, and timing relative to menopause
Rough handling, contamination, or improper technique can reduce potency or introduce bacteria into a solution you will be injecting into your body
doi: 10.2337/dc19-0883
It might run, but you are driving blind, and the small changes add up to significant failures
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