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F., Kochhar, P., Jasper, S., Brotherton, B., Orban, B., & Lulic, Z

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The non-canonical NF-B pathway is activated by a specific group of stimuli, such as CD40 ligand, CD27 ligand, BAFF, human T-cell leukemia virus, and other stimuli

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Genetic targeting of TCF4 or using bromodomain and extra-terminal motif (BET) inhibitors has been shown to enhance melanoma cell recognition by T cells in co-culture experiments, increasing the sensitivity of melanoma lesions to ICB in mouse models (6264)

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