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The amylin pathway research that preceded tirzepatide laid groundwork for understanding how multiple hormonal signals can be targeted simultaneously for enhanced metabolic control
While beneficial for patients with obesity and metabolic syndrome, unintended weight loss can be detrimental in Crohn's disease patients who already struggle with malnutrition, malabsorption, or disease-related cachexia
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This is consistent with reports indicating that a small but significant subpopulation of baratric surgery patients drinks more alcohol after the surgery
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