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Importantly, the study also showed significant reductions in HbA1c, fasting glucose, triglycerides, and liver fat content across dose groups, suggesting multi-organ metabolic improvement beyond weight loss alone

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The work was carried out in the School of Biomedical Sciences, The University of Sydney during the period June 2005 to February 2006

Cancer Res 54 : 55315534 Karnieli E, Werner H, Rauscher II FJ, Benjamin LE, LeRoith D (1996) The IGF-I receptor gene promoter is a molecular target for the Ewing's sarcoma-Wilms' tumor 1 fusion protein