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Cost of medication AED 1,734 AED 743 AED 743 Scientific name Tirzepatide (dual GIP + GLP-1 receptor agonist) Semaglutide (GLP-1 receptor agonist) Semaglutide (GLP-1 receptor agonist) Blood Panel Chronic weight management in adults with BMI 30 or BMI 27 with at least 1 metabolic condition, e.g., diabetes, hypertension Chronic weight management in adults & adolescents 12 years with BMI 30 or BMI 27 with at least 1 comorbidity Type 2 diabetes Expected weight loss based on studies -21% at 72 weeks based on the SURMOUNT-1 study -15% at 68 weeks based on the STEP-1 study Similar to Wegovy Reduction in diabetes markers Results from SURPASS-CVOT study pending SELECT trial: 20 % MACE over ~3 y

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