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It's only been 20 years since GLP-1 medications got FDA approval for diabetes, and their approval for weight management is even more recent

It works best alongside a healthy diet and regular exercise

These usually occur during the dose-escalation phase and tend to diminish over time. Patients can improve tolerability by consuming smaller portions and avoiding high-fat or spicy meals. Dosing should start low and be increased gradually based on tolerance and clinical goals. Administration and Storage Considerations Injectable agents such as dulaglutide and semaglutide must be refrigerated before the first use

Spread it out: sip during and between meals, not just all at once