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TPL disrupts mitochondrial membrane potential by modulating Bcl-2 family proteins (e.g., upregulating Bax/Bak and downregulating Bcl-2/Bcl-xL), triggering cytochrome C release and subsequent activation of the caspase-9/caspase-3 cascade (Li X

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By activating GLP-1, GIP, and glucagon receptors, it enables researchers to examine how overlapping endocrine systems regulate glucose uptake, nutrient distribution, and cellular energy utilization

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The synthesis of glutathione involves two enzymatic steps, both requiring ATP hydrolysis for energy supply

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