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Oral lesions presented each as an asymptomatic pigmented dark-brown macule with an intact mucosal surface and well-defined borders, except case 2

The standard schedule increases the dose every four weeks, from 0.25 mg up to the 2.4 mg maintenance dose over about 16 weeks

Fibromyalgia: a clinical review

Trials are ordered chronologically and added sequentially, so that each line represents the updated pooled estimate after inclusion of each additional study