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DDIs occur when one drug alters the pharmacokinetics or pharmacodynamics of another, leading to: Increased toxicity Reduced efficacy Unexpected clinical outcomes Most clinically relevant DDIs are mechanism-driven, not accidental

Coppola P, da Silva FG, Gomide G, Paula FLO, Campos AFC, Perzynski R, Kern C, Depeyrot J, Aquino R (2016) Hydrothermal synthesis of mixed zinc-cobalt ferrite nanoparticles: structural and magnetic properties

With these symptoms, documenting what you observe and when makes sense

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