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In contrast, in a pre-clinical study, combining HFD and STZ treatment in ApoE / failed to detect evidence for GLP-1R-dependent reduction of lesion size in the thoracic or abdominal aorta (168)
These findings suggest that simultaneous engagement of GIP, GCG, and GLP-1 receptors in humans may offer a significant therapeutic advantage in the management of T2DM [104]
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D.McQuarrieA.TangA.GriffinM.et al (2024)
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