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A lower pool of this antioxidant may lead to more oxidative damage in the skin and can contribute to dullness or uneven tone

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The activity of glutathione-epothilone conjugate was higher than staurosporine by about 8 folds, ensuring the superior cytotoxic efficiency of the conjugate

Further mechanistic studies have found that treatment with TMZ promoted cardiac Nrf2 expression, indicating that TMZ enhanced the clearance of oxidative stress by activating the GSH system through the Nrf2 signaling pathway [210]