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1. Tone refinement (clarity signal): Niacinamide supports a more even-looking surface and helps reduce the look of tone irregularities that create visual distraction
Importantly, B12 deficiency can occur without anaemia, and some patients may present with neurological symptoms despite having normal haemoglobin levels
Also anyone with known environmental exposures, a history of amalgam fillings, high fish consumption, or occupational heavy metal contact
This has made it a widely used research tool in skin biology and connective tissue research
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