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Peptides 39 , 7179, doi:10.1016/j.peptides.2012.10.006 (2013)
The drug reaches peak concentration in the blood within three to four hours and has a half-life of roughly 20 hours, which explains why a single morning dose can suppress appetite through most of the day
Avoid greasy, spicy, or highly acidic foods, which can exacerbate GI distress
Because combination drugs have fixed ratios of their active ingredients, it may be more difficult to adjust the dosages than if you were taking metformin and the other drug as two separate pills
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